Correlation of Carboxyhemoglobin Level with Alanine Aminotransferase Enzyme Level in Satay Traders

Abstract

Carbon monoxide is a hazardous pollutant that results from incomplete combustion. Satay vendors are at risk because their daily activities interact with smoke from burning charcoal and other hazardous pollutants in the work environment. The more CO that is inhaled, it will form COHb in the body in large quantities which can cause hypoxia of liver tissue. This study aimed to determine the correlation of carboxyhemoglobin levels with alanin aminotransferase levels in satay traders. This was an analytic observational study with a cross-sectional approach. The population of this study were satay vendors who traded near the highway in the Gubeng Subdistrict area of Surabaya City with a total sample size of 20 which was determined by purposive sampling. Data collection used primary data by examining test materials at the Clinical Toxicology Laboratory of the Department of Medical Laboratory Technology of Poltekkes Kemenkes Surabaya and the Bakti Analysis Laboratory in April - May 2023. The results of the examination of carboxyhemoglobin levels and alanin aminotransferase levels showed that all samples were below the normal threshold with an average COHb of 0.91% and an average alanin aminotransferase level of 40.0 U/L. From the Spearman correlation test, the p-value = 0.015 and r = 0.536. It can be concluded that there is a high positive correlation between carboxyhemoglobin levels and alanin aminotransferase levels in satay traders.

Keywords: carboxyhemoglobin level; alanin aminotransferase level; satay vendors